Tissue engineering majorly they are used in Organ Transplantation and Therapeutic Cloning like Bio Artificial liver device, artificial pancreas, artificial bladders, and Cartilage. When there is damage in our body cells or organs, we use tissue-engineering techniques to overcome the damage by replacing the old cell. There is wide range of Tissue Engineered product or materials, which are used to cure diseases in human and save life.
Regenerative Medicine is focused on emerging and applying new treatments to heal tissues and organs and restore function absent due to aging, disease, injury or defects. The human body has the natural ability to heal itself in many ways.
In Biology, Tissue is a cellular organizational level between cells and a complete organ. A Tissue is an ensemble of similar cells and their extracellular matrix from the same origin that together carry out a specific function. Organs are then formed by the functional grouping together of multiple tissues.
Three-dimensional (3D) Printing, also known as additive manufacturing or rapid prototyping, plays an important role in tissue engineering applications where the goal is to produce scaffolds to repair or replace damaged tissues and organs
Tissue culture techniques offer us the opportunity to maintain distinguished gene lineage. When preserved with tissue culture, genes are in a kind of animated suspension and can be left in tissue banks for prolonged periods. The tissue culture technique can be used for mass propagation of plants with the same genetic expression.
Stem cells that can be used for tissue regeneration include mesenchymal stem cells, embryonic stem cells, and induced pluripotent stem cells. Decades of research has allowed us to glimpse the potential of stem cells to treat disease. It is possible they will give us life-changing therapies for multiple sclerosis, type 1 diabetes, Parkinson's disease and macular degeneration
Few tissue markers are currently available to pathologists in the study of hepatocellular tumors. These markers should be used carefully taking into consideration not only morphology but also, and sometimes even more important, the clinical setting where the lesion to be diagnosed had developed. Various types of molecules, such as DNA (genes), proteins or hormones, can serve as biomarkers, since they all indicate something about your health. Biomarkers may be produced by the cancer tissue itself or by other cells in the body in response to cancer.
Nanotechnology is a powerful strategy in tissue regeneration for recreating the nanoscale features of tissues that can direct cellular adhesion, migration, and differentiation. In addition, we will discuss nanotechnology-based approaches for treating bone, muscle, cardiovascular, and neural tissue diseases
Stem cell therapy holds immense promise for the treatment of patients with diabetes mellitus. Research on the ability of human embryonic stem cells to differentiate into islet cells has defined the developmental stages and transcription factors involved in this process
Stem cells survive much longer than ordinary cells, increasing the chance that they might accumulate genetic mutations. It might take only a few mutations for one cell to lose control over its self-renewal and growth and become the source of cancer
The future of regenerative medicine include stimulating endogenous stem cells for in situ repair, transplantation of organoids to repair minor tissue injury, and the use of interspecies chimerism to produce functional metabolic organs for transplantation
Regenerative Medicine is focused on developing and applying new treatments to heal tissues and organs and restore function lost due to aging, disease, damage or defects. The human body has the natural ability to heal itself in many ways
Tissue regeneration is a part of the organism's tissue that is traumatized by external forces and partially lost. Based on the remaining part, it grows the same structure and function as the lost part. This repair process is called tissue regeneration
Biological materials such as collagen, various proteoglycans, alginate-based substrates and chitosan have all been used in the production of scaffolds for tissue engineering. Unlike synthetic polymer-based scaffolds, natural polymers are biologically active and typically promote excellent cell adhesion and growth
Immunotherapy is a type of cancer treatment that helps your immune system fight cancer. The immune system helps your body fight infections and other diseases. It is made up of white blood cells and organs and tissues of the lymph system. Immunotherapy is a type of biological therapy.
Cord blood stem cells are a precious resource that have been saving lives for more than three decades. Since 1988, there have been more than 1 million stem cell treatments worldwide6 and umbilical cord blood stem cells are the recognised therapy for over 80 diseases.12 These include various cancers, blood and immune disorders
Stem cells are not only used for regenerative medicine but are also considered as a useful tool for cancer treatment. For a long time, stem cells have been utilized to renew the immune system for radiation or chemotherapy-treated patients. Recently, stem cells are being engineered to carry therapeutic reagents to target tumour sites. Cancer vaccines depend on the knowledge of cancer stem cells that have been studied and applied for cancer treatment. In- induced pluripotent stem cells have been used to create active T cells to support cancer immunotherapy. Those all are due to the unique characteristics of stem cells, like immunological tolerance, migration, and tissue reparation.
In tissue engineering applications, Muscle-derived stem cell particularly those genetically engineered to express growth factors have been demonstrated to possess great potential for the regeneration and for the repair of bone, muscle, and cartilage. greatly enhance the usefulness of muscle-derived stem cells, as well as other adult stem cells, for regeneration applications and tissue repair.
Bioreactor systems play an important role in tissue engineering, as they enable reproducible and controlled changes in specific environmental factors. They can provide technical means to perform controlled studies aimed at understanding specific biological, chemical or physical effects.
Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biological tissues
Biomaterials are key components in tissue engineering and regenerative medicine applications, with the intended purpose of reducing the burden of disease and enhancing the quality of life of a large number of patients
Biochips refer to the complete fundamental functional unit, capable of performing multi biochemical tasks simultaneously. Tissue chips on the other hand are similar miniaturized units that can replace a tissue or some part of it, enabling the organ to work normally. Both biochips & tissue chips have been elemental in tissue engineering technology and have proven to be of utmost importance in the same arena. DNA microarray also called as biochip in simple terms consists of a two dimensional grid system where upon sensors or solid flat substrates are incorporated. These solid substrates can be either positively charged just like silicon or glass or can also be consisting of integrated circuitry units that perform best in signal transduction studies. These sorts of microarrays have application in micromechanical studies.
Heart Disease is the leading cause of death in the world. Recent clinical trials and laboratory experiments suggest that cell therapies can improve cardiac function. Bone marrow-derived progenitor cells and other progenitor cells can differentiate into vascular cell types, restoring blood flow. Resident cardiac stem cells have been shown to differentiate into multiple cell types present in the heart, along with cardiac muscle cells, indicating that the heart is not terminally differentiated. These new findings have stimulated optimism that the progression of heart failure can be reversed with this technique